Clinical reference
Anticoagulant · Unfractionated heparin (UFH) · Neonatology, Hematology, Critical Care, Cardiology
Unfractionated heparin for neonatal ECMO anticoagulation (100 units/kg IV load then infusion titrated to ACT 180–220 sec), catheter patency (central line 0.5 units/kg/hr; peripheral 0.5–1 unit/mL in IV fluids), and thrombosis treatment (75 units/kg IV load then 28 units/kg/hr; target anti-Xa 0.3–0.7 units/mL). Confirm vial concentration to prevent fatal d…