Clinical reference
Hemostatic · Recombinant activated coagulation factor VII · Hematology, Pediatrics, Surgery
Recombinant factor VIIa for bleeding in hemophilia A/B with inhibitors, congenital factor VII deficiency, and Glanzmann's thrombasthenia; also used off-label as rescue for refractory bleeding (e.g., cardiac surgery). IV bolus 90 mcg/kg q2h (hemophilia/Glanzmann) or 15–30 mcg/kg q4–6h (factor VII deficiency) until hemostasis. Black box warning: serious thr…