Clinical reference
Antibiotic · Cephalosporin with beta-lactamase inhibitor · Infectious Disease, Critical Care, Pediatrics
Ceftolozane/tazobactam (Zerbaxa) combines a cephalosporin with a beta-lactamase inhibitor. Injection: 1 g ceftolozane and 0.5 g tazobactam per vial; contains 600 mg L-arginine and ~8.3 mEq sodium per gram of ceftolozane. All doses are based on the ceftolozane component and infused over 1 hr. Use is reserved for multidrug-resistant Gram-negative infections…