Clinical reference
Antibiotic · Cephalosporin (third generation) · Infectious Disease, Pediatrics, Critical Care
Cefotaxime is a third-generation cephalosporin. Injection: 1, 2 g vials; each gram contains ~2.2 mEq sodium. Use with caution in penicillin-allergic patients and in renal impairment (reduce dosage; see Chapter 31). Good CNS penetration. Toxicities similar to other cephalosporins: allergy, neutropenia, thrombocytopenia, eosinophilia, false-positive urine-r…