Clinical reference
Antiviral · Antiviral agent (prodrug of acyclovir) · Infectious Diseases, Dermatology, Pediatrics
Valacyclovir is an antiviral prodrug metabolized to acyclovir and L-valine with better oral absorption than acyclovir. Formulations: tablets/caplets 500, 1000 mg; oral suspension 50 mg/mL. Use with caution in hepatic or renal insufficiency (adjust dose; see Chapter 31). TTP/HUS reported in advanced HIV, bone marrow and renal transplant recipients. Probene…