Clinical reference
Non-pharmacologic / Sweetener · Procedural pain relief ·
Sucrose (12–24% solution) is used for mild analgesia and behavioral comforting prior to painful procedures (e.g. vaccination, heel lances) in preterm and term infants. Administer directly to the tongue 2 minutes prior to procedure; pacifier may be offered after or dipped in sucrose 2 min prior. Sweet-Ease® is a 24% sucrose solution in a 15 mL cup.