Clinical reference
Antithyroid agent · Thionamide · Endocrinology, Pediatrics, Internal Medicine
Propylthiouracil (PTU) is a thionamide antithyroid drug used for the management of hyperthyroidism. It is generally reserved for patients who cannot tolerate methimazole and for whom radioactive iodine or surgery are not appropriate, and is considered the antithyroid treatment of choice during or just prior to the first trimester of pregnancy due to methi…