Clinical reference
Uricosuric / Penicillin adjuvant · Penicillin therapy adjuvant, uric acid–lowering agent · Infectious Diseases, Rheumatology, Pediatrics
Probenecid is used to prolong penicillin levels, to lower uric acid in gout, and as an antibiotic adjunct in gonorrhea; it is also used for prevention of cidofovir nephrotoxicity (see Cidofovir). Tablets: 500 mg. Use with caution in peptic ulcer disease. Contraindicated in children <2 yr and in renal insufficiency. Do not use if GFR <30 mL/min. Inhibits r…