Clinical reference
Respiratory · Selective pulmonary vasodilator · Neonatology, Pediatrics, Critical care, Pulmonology
Inhaled nitric oxide for hypoxic respiratory failure associated with pulmonary hypertension in term and near-term infants >34 wk gestation. 20 ppm (max 20 ppm); wean to 5 ppm then 1 ppm increments. Reduces need for ECMO when OI >25. Administer via calibrated delivery system; taper to avoid rebound. Not recommended for BPD prevention in preterm.