Clinical reference
Cystic fibrosis therapy · CFTR corrector (elexacaftor, tezacaftor) and potentiator (ivacaftor) combination · Pulmonology, Cystic Fibrosis, Pediatrics
Elexacaftor/tezacaftor/ivacaftor (Trikafta) is a combination of two cystic fibrosis transmembrane conductance regulator (CFTR) correctors (elexacaftor and tezacaftor) and a CFTR potentiator (ivacaftor) used for treatment of cystic fibrosis in patients with at least one F508del CFTR mutation. Tablets are taken in the morning and evening with fat-containing…