Clinical reference
Gastrointestinal · H2-receptor antagonist · Gastroenterology, Critical Care, Pediatrics
Cimetidine is an H2-receptor antagonist. Dose 2.5–5 mg/kg/dose every 6–12 hours PO or IV over 15–20 minutes. Used for prevention and treatment of stress ulcers and GI hemorrhage. Contraindicated with cisapride. Do not use for apnea of prematurity, crying/irritability in healthy term infants, or uncomplicated GER; risks may outweigh benefits in preterm inf…