Clinical reference
Antidepressant · Tricyclic antidepressant (TCA) · Psychiatry, Neurology, Pediatrics, Pain Medicine
Amitriptyline is a tricyclic antidepressant. Formulations: Tablets 10, 25, 50, 75, 100, 150 mg; Oral suspension 10 mg/mL, 20 mg/mL; Oral syrup 1 mg/mL. See remarks for pharmacogenomic considerations (CYP 2D6 and 2C19). T1/2 9–25 hr in adults. Maximum antidepressant effects may not occur for 2 wk or more after initiation. Do not abruptly discontinue in pat…